E3 Ligase Ligand-linker Conjugate 130
Product Specifications
UNSPSC Description
E3 Ligase Ligand-linker Conjugate 130 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 130 can be used to synthesize YJ1206 (HY-16855)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-130.html
Smiles
FC(C=C(C(N(C1CCC(NC1=O)=O)C2=O)=O)C2=C3)=C3N4CCC(O)CC4
Molecular Weight
375.35
References & Citations
[1]Chang Y, et al. Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition. Cell Rep Med. 2024 Oct 15;5(10):101752.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168659/E3-Ligase-Ligand-linker-Conjugate-130-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168659/
Clinical Information
No Development Reported
Curated Selection
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