22-NBD-Cholesterol (Highly Pure)

<strong>22-NBD-Cholesterol (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2018509_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 494.64_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 22-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-23,24-bisnor-5-cholen-3β-ol_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lajdova I, Ovsonkova L, Spustova V, Oksa A, Chorvat D, Mateasik A, Marcek Chorvatova A. Spectrally and Time-Resolved Fluorescence Imaging of 22-NBD-Cholesterol in Human Peripheral Blood Mononuclear Cells in Chronic Kidney Disease Patients Molecules. 2021 Nov 11;26(22):6800._x000D_ 2: Faletrov YV, Bialevich KI, Edimecheva IP, Kostsin DG, Rudaya EV, Slobozhanina EI, Shkumatov VM. 22-NBD-cholesterol as a novel fluorescent substrate for cholesterol-converting oxidoreductases J Steroid Biochem Mol Biol. 2013 Mar;134:59-66._x000D_ 3: Ishii H, Shimanouchi T, Umakoshi H, Walde P, Kuboi R. Analysis of the 22-NBD-cholesterol transfer between liposome membranes and its relation to the intermembrane exchange of 25-hydroxycholesterol Colloids Surf B Biointerfaces. 2010 May 1;77(1):117-21._x000D_ 4: Ostašov P, Sýkora J, Brejchová J, Olżyńska A, Hof M, Svoboda P. FLIM studies of 22- and 25-NBD-cholesterol in living HEK293 cells: plasma membrane change induced by cholesterol depletion Chem Phys Lipids. 2013 Feb-Mar;167-168:62-9._x000D_ 5: Robalo JR, Ramalho JP, Loura LM. NBD-labeled cholesterol analogues in phospholipid bilayers: insights from molecular dynamics J Phys Chem B. 2013 Nov 7;117(44):13731-42._x000D_ 6: Tugaeva KV, Faletrov YV, Allakhverdiev ES, Shkumatov VM, Maksimov EG, Sluchanko NN. Effect of the NBD-group position on interaction of fluorescently-labeled cholesterol analogues with human steroidogenic acute regulatory protein STARD1 Biochem Biophys Res Commun. 2018 Feb 26;497(1):58-64._x000D_ 7: Guo Y, Liu B, Geng Y, Chen K, Li J, Yin X, Zhang S. Fisetin, a dietary flavonoid, promotes transintestinal cholesterol excretion through the activation of PPARδ Food Res Int. 2024 Jan;175:113783._x000D_ 8: Faletrov Y, Brzostek A, Plocinska R, Dziadek J, Rudaya E, Edimecheva I, Shkumatov V. Uptake and metabolism of fluorescent steroids by mycobacterial cells Steroids. 2017 Jan;117:29-37._x000D_ 9: Igarashi F, Ogihara MH, Iga M, Kataoka H. Cholesterol internalization and metabolism in insect prothoracic gland, a steroidogenic organ, via lipoproteins Steroids. 2018 Jun;134:110-116._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36713845">10: Zhang C, Wu X, Shi P, Ma H, Fang F, Feng Q, Zhao S, Zhang R, Huang J, Xu X, Xiao W, Cao G, Ji X. Diterpenoids inhibit ox-LDL-induced foam cell formation in RAW264.7 cells by promoting ABCA1 mediated cholesterol efflux Front Pharmacol. 2023 Jan 12;14:1066758. </a>_x000D_ _x000D_ <strong>Products Related to 22-NBD-Cholesterol (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Lipids/"> Lipids</a>