Human CASP2 Protein

<strong>Human CASP2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011697_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1.0 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Caspase 2 isoform 1 protein, CASP-2 protein, ICH1 protein, NEDD-2 protein, NEDD2 protein, PPP1R57 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Eddy SR. Profile hidden Markov models Bioinformatics. 1998;14(9):755-63._x000D_ 2: Ning X, Wang Y, Jing M, Sha M, Lv M, Gao P, Zhang R, Huang X, Feng JM, Jiang Z. Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3 Mol Cell. 2019 Apr 4;74(1):19-31.e7._x000D_ 3: Vigneswara V, Ahmed Z. Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2 Cell Death Dis. 2019 Feb 4;10(2):102._x000D_ 4: Kopeina GS, Zhivotovsky B. Caspase-2 as a master regulator of genomic stability Trends Cell Biol. 2021 Sep;31(9):712-720._x000D_ 5: Dorstyn L, Kumar S. Caspase-2 protocols Methods Mol Biol. 2014;1133:71-87._x000D_ 6: Bouchier-Hayes L, Green DR. Caspase-2: the orphan caspase Cell Death Differ. 2012 Jan;19(1):51-7._x000D_ 7: Parsons MJ, McCormick L, Janke L, Howard A, Bouchier-Hayes L, Green DR. Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice Cell Death Differ. 2013 Sep;20(9):1174-82._x000D_ 8: Carlsson Y, Schwendimann L, Vontell R, Rousset CI, Wang X, Lebon S, Charriaut-Marlangue C, Supramaniam V, Hagberg H, Gressens P, Jacotot E. Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury Ann Neurol. 2011 Nov;70(5):781-9._x000D_ 9: Yang L, Dou Y, Sui Z, Cheng H, Liu X, Wang Q, Gao P, Qu Y, Xu M. Upregulated miRNA-182-5p expression in tumor tissue and peripheral blood samples from patients with non-small cell lung cancer is associated with downregulated Caspase 2 expression Exp Ther Med. 2020 Jan;19(1):603-610._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32811973">10: Lim Y, De Bellis D, Sandow JJ, Capalbo L, D'Avino PP, Murphy JM, Webb AI, Dorstyn L, Kumar S. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function Cell Death Differ. 2021 Jan;28(1):349-366. </a>_x000D_ _x000D_ <strong>Products Related to Human CASP2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>