Casein

Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials[1][2][3][4][5][6].

Product Specifications

CAS Number

[9000-71-9]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Casein Kinase; Endogenous Metabolite

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Stem Cell/Wnt

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/casein.html

Purity

97.40

Solubility

0.1 M NaOH : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[Casein]

Molecular Formula

C81H125N22O39P

Molecular Weight

2061.96

Precautions

H302, H315, H319, H335

References & Citations

[1]Ghosh A, et al. Effect of cross-linking on microstructure and physical performance of casein protein. Biomacromolecules. 2009;10 (7) :1681-1688.|[2]Park SW, et al. A milk protein, casein, as a proliferation promoting factor in prostate cancer cells. World J Mens Health. 2014 Aug;32 (2) :76-82.|[3]Rosenberg E, et al. Cell density-dependent growth of Myxococcus xanthus on casein. J Bacteriol. 1977 Feb;129 (2) :770-7.|[4]Lillefosse HH, et al. Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice. J Nutr. 2013 Sep;143 (9) :1367-75.|[5]Bennett T, et al. The effect of high intakes of casein and casein phosphopeptide on calcium absorption in the rat. Br J Nutr. 2000 Jun;83 (6) :673-80.|[6]Reynolds EC, et al. Effect of casein and whey-protein solutions on caries experience and feeding patterns of the rat. Arch Oral Biol. 1984;29 (11) :927-33.