(R) -JAK2/STAT3-IN-1
(R) -JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R) -JAK2/STAT3-IN-1 can inhibit the phosphorylation of JAK2 and STAT3. The affinity of (R) -JAK2/STAT3-IN-1 for GP130 protein is 3.8 μM. (R) -JAK2/STAT3-IN-1 effectively inhibits the viability and migration of tumor cells and promotes apoptosis[1].
Product Specifications
CAS Number
[2485758-49-2]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-jak2-stat3-in-1.html
Smiles
NC(N1[C@H](CC(C2=CC=C(C=C2)C(F)(F)F)=N1)C(C3=C4)=CN(CC5=CC=C(C=C5)OCCN6CCCCCC6)C3=CC=C4Br)=O
Molecular Formula
C34H35BrF3N5O2
Molecular Weight
682.57
References & Citations
[1]Discovery of bazedoxifene analogues targeting glycoprotein 130
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit Anti Human SIM2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(Western Blot)
Rabbit Anti Human SIM2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(Western Blot)
Rabbit Anti Human SIM2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(Western Blot)
Bovine UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) ELISA Kit
