Desotamide

Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively) .

Product Specifications

CAS Number

[194660-14-5]

Product Name Alternative

Desotamide A

UNSPSC

12352209

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/desotamide.html

Smiles

O=C(N[C@H](C(N[C@@H](C(N[C@@]1([H])[C@H](C)CC)=O)CC(C)C)=O)CC(C)C)[C@@H](NC(CNC([C@@H](NC1=O)CC(N)=O)=O)=O)CC2=CNC3=CC=CC=C23

Molecular Formula

C35H52N8O7

Molecular Weight

696.84

References & Citations

[1]Miao, et al. Inhibition of bacterial RNA polymerases. Peptide metabolites from the cultures of Streptomyces sp. J. Nat. Prod. 60 (8), 858-861 (1997) .