Cynomolgus PADI4 Protein, His Tag (active enzyme)
Cynomolgus PADI4 Protein, His Tag (PA4-C5143) is expressed from E. coli cells. It contains AA Met 1 - Pro 663 (Accession # A0A2K5USI5-1) .
Product Specifications
Background
Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76.1 kDa. The protein migrates as 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
Accession Number
A0A2K5USI5-1
Expression Region
Met 1 - Pro 663
Host
E. coli
Target
PADI4
Conjugation
Unconjugated
Tag
N-10xHis
Source
Cynomolgus
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Liquid
Buffer
500 mM NaCl, pH8.0
Additives
Glycerol
Molecular Weight
76.1 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/PA4-C5143.pdf
Species
Cynomolgus
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