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Cynomolgus PADI4 Protein, His Tag (active enzyme)

Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.

Product Specifications

Background

Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76.1 kDa. The protein migrates as 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

A0A2K5USI5-1

Expression Region

Met 1 - Pro 663

Host

E. coli

Target

PADI4

Conjugation

Unconjugated

Tag

N-10xHis

Source

Cynomolgus

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

500 mM NaCl, pH8.0

Additives

Glycerol

Molecular Weight

76.1 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

E. coli

Species

Cynomolgus

Protein ID

A0A2K5USI5-1

Preservative

Glycerol

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