Kemptide

Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA) .

Product Specifications

CAS Number

[65189-71-1]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

PKA

Type

Peptides

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Kemptide.html

Purity

98.9

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(O)CNC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)N)=O)=O)=O)=O)=O)=O

Molecular Formula

C32H61N13O9

Molecular Weight

771.91

Precautions

H302, H315, H319, H335

References & Citations

[1]Kübler D, et al. Evidence for ecto-protein kinase activity that phosphorylates Kemptide in a cyclic AMP-dependent mode. J Biol Chem. 1989 Aug 25;264 (24) :14549-55.|[2]Duncan FE, et al. Transducin-like enhancer of split-6 (TLE6) is a substrate of protein kinase A activity during mouse oocyte maturation. Biol Reprod. 2014 Mar 20;90 (3) :63.