SDZ 216-525
Product Specifications
UNSPSC Description
SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor[1][2].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sdz-216-525.html
Smiles
O=C(C(N1)=CC2=C1C=CC=C2N3CCN(CCCCN(C(C4=C5C=CC=C4)=O)S5(=O)=O)CC3)OC
Molecular Weight
496.58
References & Citations
[1]Boddeke H W G M, et al. Agonist/antagonist interactions with cloned human 5-HT 1A receptors: variations in intrinsic activity studied in transfected HeLa cells[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1992, 345: 257-263.|[2]Sharp T, et al. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo[J]. British journal of pharmacology, 1993, 109(3): 699-702.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116309/SDZ-216-525-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116309/
Clinical Information
No Development Reported
CAS Number
141533-35-9
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