Thymol

Thymol is a TRPA1 agonist. Thymol induces cancer cell apoptosis. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects[1].

Product Specifications

CAS Number

[89-83-8]

UNSPSC

12352005

Hazard Statement

H302, H314, H411

Target

Apoptosis; Bacterial; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/thymol.html

Purity

99.97

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC(C)=CC=C1C(C)C

Molecular Formula

C10H14O

Molecular Weight

150.22

Precautions

H302, H314, H411

References & Citations

[1]Marchese A, et al. Antibacterial and antifungal activities of thymol: A brief review of the literature. Food Chem. 2016 Nov 1;210:402-14.|[2]Li T, et al. Thymol targeting interleukin 4 induced 1 expression reshapes the immune microenvironment to sensitize the immunotherapy in lung adenocarcinoma. MedComm (2020) . 2023 Aug 30;4 (5) :e355.|[3]De La Chapa JJ, et al. Thymol inhibits oral squamous cell carcinoma growth via mitochondria-mediated apoptosis. J Oral Pathol Med. 2018 Aug;47 (7) :674-682. |[4]Hu LB, et al. Thymol Induces Conidial Apoptosis in Aspergillus flavus via Stimulating K+ Eruption. J Agric Food Chem. 2018 Aug 15;66 (32) :8530-8536.