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Chelidonine (Standard)

Chelidonine (Standard) is the analytical standard of Chelidonine. This product is intended for research and analytical applications. Chelidonine, an isoquinoline alkaloid, can be isolated from Chelidonium majus L.. Chelidonine causes G2/M arrest and induces caspase-dependent and caspase-independent apoptosis, and prevents cell cycle progression of stem cells in Dugesia japonica. Chelidonine has cytotoxic activity against melanoma cell lines. with anticancer and antiviral activity[1][2][3].

Product Specifications

CAS Number

476-32-4

UNSPSC

12352005

Target

Apoptosis; Influenza Virus; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Others

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/chelidonine-standard.html

Smiles

CN1[C@@]2([H])[C@@]([C@H](CC3=C2C=C4C(OCO4)=C3)O)([H])C5=C(C6=C(OCO6)C=C5)C1

Molecular Formula

C20H19NO5

Molecular Weight

353.37

References & Citations

[1]Lee YK, et al. Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G2/M Arrest in the T98G Human Glioblastoma Cell Line. Evid Based Complement Alternat Med. 2019 May 26;2019:6318179.|[2]Isolani ME, et al. The in vivo effect of chelidonine on the stem cell system of planarians. Eur J Pharmacol. 2012 Jul 5;686 (1-3) :1-7.|[3]Hammerová J, et al. Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status. J Dermatol Sci. 2011 Apr;62 (1) :22-35.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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