Niclofolan

Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection[1][2][3].

Product Specifications

CAS Number

[10331-57-4]

Product Name Alternative

BAY 9015; Menichlopholan; Menichlofolan; Bilevon

UNSPSC

12352005

Hazard Statement

H302, H315, H317, H318, H410

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/niclofolan.html

Purity

99.55

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=[N+](C1=C(O)C(C2=C(O)C([N+]([O-])=O)=CC(Cl)=C2)=CC(Cl)=C1)[O-]

Molecular Formula

C12H6Cl2N2O6

Molecular Weight

345.09

Precautions

H302, H315, H317, H318, H410

References & Citations

[1]T Eckhardt, Treatment of human fascioliasis with niclofolan. Gastroenterology. 1981 Oct; 81 (4) :795-8. |[2]B H Ali, T Hassan, et al. The effect of niclofolan on desert sheep experimentally infected with immature Fasciola gigantica. J Vet Pharmacol Ther. 1985 Dec;8 (4) :398-403. |[3]Santamarina M. T., et al. Anthelmintic treatment against Gyrodactylus sp. infecting rainbow trout Oncorhynchus mykiss. Diseases of Aquatic Organisms, 1991 10 (1) : 39-43. |[4]Rim H J, et al. Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis. The Korean Journal of Parasitology, 1976, 14 (2) : 140-146.