PRT4165
Product Specifications
UNSPSC Description
PRT4165 is a potent inhibitor of polycomb-repressive complex 1 (PRC1)-mediated H2A ubiquitylation.
Target Antigen
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PRT4165.html
Purity
98.0
Smiles
O=C1/C(C(C2=C1C=CC=C2)=O)=C/C3=CC=CN=C3
Molecular Weight
235.24
References & Citations
[1]Ismail IH, et al. A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks. J Biol Chem. 2013 Sep 13;288(37):26944-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19817/PRT4165-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19817/PRT4165-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
31083-55-3
Available Sizes
Curated Selection
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