PRT4165
PRT4165 is a potent inhibitor of polycomb-repressive complex 1 (PRC1) -mediated H2A ubiquitylation.
Product Specifications
CAS Number
[31083-55-3]
Product Name Alternative
NSC600157
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PRT4165.html
Concentration
10mM
Purity
98.0
Smiles
O=C1/C(C(C2=C1C=CC=C2)=O)=C/C3=CC=CN=C3
Molecular Formula
C15H9NO2
Molecular Weight
235.24
Precautions
H315, H319, H320
References & Citations
[1]Ismail IH, et al. A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks. J Biol Chem. 2013 Sep 13;288 (37) :26944-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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