PHC1 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to PHC1. Polyhomeotic-like protein 1 (PHC1) is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.

Product Specifications

Product Name Alternative

Anti Polyhomeotic-like protein 1 antibody, anti hPH1 antibody, anti Early development regulatory protein 1 antibody, anti EDR1 antibody, anti PH1 antibody

UniProt

P78364

Reactivity

Human

Immunogen

C-terminal region of human PHC1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Stem Cell & Developmental Biology

Concentration

100 μg/ml BSA

Dilution

WB:1:1:000-1:3:000, IF/ICC:1:100-1:200

Purity

Affinity purification

Molecular Weight

106

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PHC1.