SRA1 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to SRA1. Steroid receptor RNA activator 1 (SRA1) was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that SRA1 is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. Both long non-coding and protein-coding RNAs are transcribed from the SRA1 gene, and they represent alternatively spliced transcript variants. The long non-coding RNA transcripts interact with a variety of proteins, including SRA1 itself. SRA1 acts as a transcriptional repressor by binding to the non-coding RNA.