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PTPN3 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to PTPN3. Tyrosine-protein phosphatase non-receptor type 3 (PTPN3) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN3 contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of PTPN3. PTPN3 was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for PTPN3.

Product Specifications

Product Name Alternative

Anti Tyrosine-protein phosphatase non-receptor type 3 antibody, anti Protein-tyrosine phosphatase H1 antibody, anti PTP-H1 antibody, anti PTPH1 antibody

UniProt

P26045

Reactivity

Human

Immunogen

C-terminal region of human PTPN3

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Signal Transduction

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

104

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PTPN3.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

Frequently Asked Questions

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