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SATB2 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to SATB2. DNA-binding protein SATB2 belongs to the CUT homeobox family. SATB2 binds to DNA, at nuclear matrix-or scaffold-associated regions. Furthermore, SATB2 is thought to recognize the sugarphosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatinloop remodeling. Also, SATB2 acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

Product Specifications

Product Name Alternative

Anti DNA-binding protein SATB2 antibody, anti Special AT-rich sequence-binding protein 2 antibody

UniProt

Q9UPW6

Reactivity

Human

Immunogen

N-terminal region of human SATB2

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

83

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SATB2.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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