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PML (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to PML. Protein PML functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. PML acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMOmediated modifications and interactions.

Product Specifications

Product Name Alternative

Anti Protein PML antibody, anti Promyelocytic leukemia protein antibody, anti RING finger protein 71 antibody, anti Tripartite motif-containing protein 19 antibody, anti MYL antibody, anti PP8675 antibody, anti RNF71 antibody, anti TRIM19 antibody

UniProt

P29590

Reactivity

Human

Immunogen

N-terminal region of human PML

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Apoptotic, Cancer, Epigenetics, Immunology, Infectious Diseases, Neuroscience, Signaling Pathways

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

98

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PML.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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