ERCC4 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to ERCC4. DNA excision repair protein ERCC4 forms a complex with ERCC1 and is involved in the 5 incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in ERCC4 are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .
Product Specifications
Product Name Alternative
Anti DNA repair endonuclease XPF antibody, anti DNA excision repair protein ERCC-4 antibody, anti RAD1 antibody, anti DNA repair protein complementing XP-F cells antibody, anti Xeroderma pigmentosum group F-complementing protein antibody, anti XPF antibody, anti ERCC11 antibody
UniProt
Q92889
Reactivity
Human
Immunogen
C-terminal region of human ERCC4
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer, DNA Damage, Epigenetics
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
104
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human ERCC4.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
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