Captodiame
Captodiame (Captodiamine) is a 5-HT2c receptor antagonist and sigma-1 and D3 dopamine receptor agonist. Captodiame shows antidepressant effect[1].
Product Specifications
CAS Number
[486-17-9]
Product Name Alternative
Captodiamine
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/captodiame.html
Smiles
CCCCSC1=CC=C(C(SCCN(C)C)C2=CC=CC=C2)C=C1
Molecular Formula
C21H29NS2
Molecular Weight
359.59
References & Citations
[1]Ring RM, et al. Captodiamine, a putative antidepressant, enhances hypothalamic BDNF expression in vivo by synergistic 5-HT2c receptor antagonism and sigma-1 receptor agonism. J Psychopharmacol. 2013;27 (10) :930-939.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Curated Selection
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