Captodiame
Captodiame (Captodiamine) is a 5-HT2c receptor antagonist and sigma-1 and D3 dopamine receptor agonist. Captodiame shows antidepressant effect[1].
Product Specifications
CAS Number
486-17-9
Product Name Alternative
Captodiamine
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/captodiame.html
Smiles
CCCCSC1=CC=C(C(SCCN(C)C)C2=CC=CC=C2)C=C1
Molecular Formula
C21H29NS2
Molecular Weight
359.59
References & Citations
[1]Ring RM, et al. Captodiamine, a putative antidepressant, enhances hypothalamic BDNF expression in vivo by synergistic 5-HT2c receptor antagonism and sigma-1 receptor agonism. J Psychopharmacol. 2013;27 (10) :930-939.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940747-500 1x 500 µL
CD66 (CEA) (COL-1 + CEA31 + C66/261), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
GAF-451-15 1 mL
Colloidal Gold Conjugated Goat Affinity Purified Antibody to Rabbit IgG, Fc Specific, 15nm
Sign In for Pricing
View Details ![MSMB Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI12F2]](https://cdn.genprice.uk/products/937/6868c3bb994c49e6dc3fd467/imageurl/ta803513am.webp)
TA803513AM 100 µL
MSMB Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI12F2]
Sign In for Pricing
View Details 
