TLR3 (M) Antibody, Rabbit Polyclonal

Rabbit polyclonal to TLR3. Toll-like receptor 3 (TLR3) belongs to the Toll-like receptor family and is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Additionally, TLR3 acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Product Specifications

Product Name Alternative

Anti Toll-like receptor 3 antibody, anti CD283 antibody

UniProt

O15455

Reactivity

Human

Immunogen

Middle region of human TLR3

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

104

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human TLR3.