CAMK2G (C2) Antibody, Rabbit Polyclonal

Rabbit polyclonal to CAMK2G. Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) belongs to the protein kinase superfamily, the CAMK Ser/Thr protein kinase family, and the CaMK subfamily. CAMK2G is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, CAMK2G is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, CAMK2G may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.