TFAP2B (N1) Antibody, Rabbit Polyclonal
Rabbit polyclonal to TFAP2B. Transcription factor AP-2-beta (TFAP2B) belongs to the AP-2 family and is a sequence-specific DNAbinding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Product Specifications
Product Name Alternative
Anti Transcription factor AP-2-beta antibody, anti AP2-beta antibody, anti Activating enhancer-binding protein 2-beta antibody
UniProt
Q92481
Reactivity
Human, Mouse
Immunogen
N-terminal region of human TFAP2B
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
50
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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