GRIN1 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to GRIN1. Glutamate receptor ionotropic, NMDA 1 (GRIN1) belongs to the glutamate-gated ion channel (TC 1.A.10.1) family and the NR1/GRIN1 subfamily. GRIN1 is an NMDA receptor subtype of glutamategated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. GRIN1 is mediated by glycine, and this protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. GRIN1 mediates neuronal functions in glutamate neurotransmission, and it is also involved in the cell surface targeting of NMDA receptors.