SREBP1 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to SREBP1. Sterol regulatory element-binding protein 1 (SREBP1) is a member of the basic helix-loop-helixleucine zipper (bHLH-Zip) transcription factor family, which is required for lipid homeostasis. SREBP1 regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. SREBP1 binds to the sterol regulatory element 1 (SRE-1) (5-ATCACCCCAC-3), and it has dual sequence specificity binding to both an E-box motif (5-ATCACGTGA-3) and to SRE-1 (5-ATCACCCCAC-3) .
Product Specifications
Product Name Alternative
UniProt
P36956
Reactivity
Human
Immunogen
C-terminal region of human SREBP1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
122
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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