IKZF3 (vPairTM) Antibodies

Rabbit polyclonal to IKZF3. IKZF3 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Zinc finger protein Aiolos (IKZF3) belongs to the Ikaros C2H2-type zinc-finger protein family. IKZF3 is a transcription factor that plays an important role in the regulation of lymphocyte differentiation. IKZF3 plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Additionally, IKZF3 is involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.