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TLR9 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to TLR9. Toll-like receptor 9 (TLR9) is a single-pass type I membrane protein belonging to the Toll-like receptor family. TLR9 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidinephosphate-guanosine (CpG) dinucleotides. TLR9 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Furthermore, TLR9 controls lymphocyte response to Helicobacter infection.

Product Specifications

Product Name Alternative

Anti Toll-like receptor 9 antibody, anti CD289 antibody, anti UNQ5798/PRO19605 antibody

UniProt

Q9NR96

Reactivity

Human

Immunogen

C-terminal region of human TLR9

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

116

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human TLR9.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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