SH3RF1 (C2) Antibody, Rabbit Polyclonal

Rabbit polyclonal to SH3RF1. E3 ubiquitin-protein ligase SH3RF1 belongs to the SH3RF family. SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) . SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Product Specifications

Product Name Alternative

Anti E3 ubiquitin-protein ligase SH3RF1 antibody, anti Plenty of SH3s antibody, anti Protein POSH antibody, anti RING finger protein 142 antibody, anti SH3 domain-containing RING finger protein 1 antibody, anti SH3 multiple domains protein 2 antibody, anti KIAA1494 antibody, anti POSH antibody, anti RNF142 antibody, anti SH3MD2 antibody

UniProt

Q7Z6J0

Reactivity

Human, Mouse

Immunogen

C-terminal region of human SH3RF1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics, Infectious Diseases

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SH3RF1.