CALD1 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to CALD1. Caldesmon (CALD1) belongs to the caldesmon family and is an actin-and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments) . CALD1 stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, CALD1 inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin.

Product Specifications

Product Name Alternative

Anti Caldesmon antibody, anti CDM antibody, anti CAD antibody

UniProt

Q05682

Reactivity

Human, Mouse

Immunogen

N-terminal region of human CALD1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Musculoskeletal & Connective Tissue Research

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human CALD1.