H-Ile-Trp-OH
H-Ile-Trp-OH (Ile-Trp), a dipeptide, is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.7 μM. H-Ile-Trp-OH inhibits predominantly the C-domain of ACE[1].
Product Specifications
CAS Number
13589-06-5
Product Name Alternative
Ile-Trp
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bnc210.html
Purity
98.04
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)[C@@H](C)CC)N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2
Molecular Formula
C17H23N3O3
Molecular Weight
317.38
Precautions
H315, H319
References & Citations
[1]Huettner C, et al. Tailoring the Adsorption of ACE-Inhibiting Peptides by Nitrogen Functionalization of Porous Carbons. Langmuir. 2019 Jul 30;35 (30) :9721-9731.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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