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H-Ile-Trp-OH

H-Ile-Trp-OH (Ile-Trp), a dipeptide, is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.7 μM. H-Ile-Trp-OH inhibits predominantly the C-domain of ACE[1].

Product Specifications

CAS Number

[13589-06-5]

Product Name Alternative

Ile-Trp

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bnc210.html

Purity

98.04

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C([C@@H](N)[C@@H](C)CC)N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2

Molecular Formula

C17H23N3O3

Molecular Weight

317.38

Precautions

H315, H319

References & Citations

[1]Huettner C, et al. Tailoring the Adsorption of ACE-Inhibiting Peptides by Nitrogen Functionalization of Porous Carbons. Langmuir. 2019 Jul 30;35 (30) :9721-9731.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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