HDAC3/8 ligand-1
HDAC3/8 ligand-1 (compound 40) is a ligand for target protein for PROTAC that can be used in the synthesis of YX968.
Product Specifications
UNSPSC
12352005
Target
HDAC; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac3-8-ligand-1.html
Smiles
CCCNNC(C(C=C1)=CC=C1N2CCNCC2)=O
Molecular Formula
C14H22N4O
Molecular Weight
262.35
References & Citations
[1]Yufeng Xiao, et al. HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation. Cell Chem Biol. 2023 Nov 16;30 (11) :1421-1435.e12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC3; HDAC8
Frequently Asked Questions
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