B7-2/CD86, Mouse (HEK293, Fc)

B7-2/CD86 Protein, Mouse (HEK293, Fc), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation[1][2].

VETQAYFNGT AYLPCPFTKA QNISLSELVV FWQDQQKLVL YEHYLGTEKL DSVNAKYLGR TSFDRNNWTL RLHNVQIKDM GSYDCFIQKK PPTGSIILQQ TLTELSVIAN FSEPEIKLAQ NVTGNSGINL TCTSKQGHPK PKKMYFLITN STNEYGDNMQ ISQDNVTELF SISNSLSLSF PDGVWHMTVV CVLETESMKI SSKPLNFTQE FPSPQTYWKE-Fc tag

[1]K S Hathcock, et al. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J Exp Med. 1994 Aug 1;180(2):631-40.|[2]S Tsuyuki, et al. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med. 1997 May 5;185(9):1671-9.