Polyalanine peptide

Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research[1].

Product Specifications

Product Name Alternative

PALA

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/polyalanine-peptide.html

Smiles

O=C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C31H53N9O12

Molecular Weight

743.81

References & Citations

[1]Radaev S, et al. Recognition of IgG by Fcγ receptor: the role of Fc glycosylation and the binding of peptide inhibitors[J]. Journal of Biological Chemistry, 2001, 276 (19) : 16478-16483.