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(S) -ZINC-3573

(S) -ZINC-3573 is an inactive enantiomer of ZINC-3573. (R) -ZINC-3573 is a selective MRGPRX2 agonist. (S) -ZINC-3573 and (R) -ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor[1].

Product Specifications

CAS Number

[2095596-11-3]

UNSPSC

12352005

Hazard Statement

H315

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-zinc-3573.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN(C)[C@@H]1CN(C2=CC(C3=CC=CC=C3)=NC4=CC=NN24)CC1

Molecular Formula

C18H21N5

Molecular Weight

307.39

Precautions

H315

References & Citations

[1]Katherine Lansu, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13 (5) :529-536.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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