(S) -ZINC-3573
(S) -ZINC-3573 is an inactive enantiomer of ZINC-3573. (R) -ZINC-3573 is a selective MRGPRX2 agonist. (S) -ZINC-3573 and (R) -ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor[1].
Product Specifications
CAS Number
[2095596-11-3]
UNSPSC
12352005
Hazard Statement
H315
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-zinc-3573.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN(C)[C@@H]1CN(C2=CC(C3=CC=CC=C3)=NC4=CC=NN24)CC1
Molecular Formula
C18H21N5
Molecular Weight
307.39
Precautions
H315
References & Citations
[1]Katherine Lansu, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13 (5) :529-536.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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