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2-Aminofluorene-d11

2-Aminofluorene-d11 is the deuterium labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].

Product Specifications

CAS Number

347841-44-5

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Purity

99

Solubility

10 mM in DMSO

Smiles

[2H]C1([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2C3=C([2H])C([2H])=C(C([2H])=C31)N([2H])[2H]

Molecular Formula

C13D11N

Molecular Weight

192.30

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Heflich RH, et al. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat Res. 1994 Oct;318 (2) :73-114. ; ; |[3]Kim BS, et al. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug Chem Toxicol. 1989 Sep-Dec;12 (3-4) :297-311.|[4]Levy GN, et al. 2-Aminofluorene-DNA adduct formation in acetylator congenic mouse lines. Carcinogenesis. 1989 Apr;10 (4) :705-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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