CHEK1 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to CHEK1.Serine/threonine-protein kinase Chk1 (CHEK1) belongs to the CAMK Ser/Thr protein kinase family.CHEK1 is required for checkpoint mediated cell cycle arrest in response to DNA damage or thepresence of unreplicated DNA. CHEK1 also acts to integrate signals from A and ATR, two cellcycle proteins involved in DNA damage responses, that also associate with chromatin in meioticprophase I. Phosphorylation of CDC25A protein phosphatase by CHEK1 is required for cells to delaycell cycle progression in response to double-strand DNA breaks.
Product Specifications
Product Name Alternative
UniProt
O14757
Reactivity
Human
Immunogen
C-terminal region of human CHEK1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:500-1:1000
Purity
Affinity purification
Molecular Weight
54
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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