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TLK1 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to TLK1.Serine/threonine-protein kinase tousled-like 1 (TLK1) belongs to the protein kinase superfamily, Ser/Thr protein kinase family. TLK1 can be rapidly and transiently inhibited by phosphorylationfollowing the generation of DNA double-stranded breaks (DSBs) during S-phase. This event is cellcycle checkpoint and A-pathway dependent and appears to regulate processes involved inchromatin assembly. TLK1 exists in several isoforms, and Isoform 3 protects the cells from theionizing radiation by faciliting the repair of DSBs.

Product Specifications

Product Name Alternative

Anti-TLK1 antibody, anti-Serine antibody, anti-threonineprotein kinase tousledlike 1 antibody, anti-PKUbeta antibody, anti-Tousledlike kinase 1 antibody, anti-KIAA0137 antibody

UniProt

Q9UKI8

Reactivity

Human, Mouse

Immunogen

N-terminal region of human TLK1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Dilution

WB:1:500-1:2000

Purity

Affinity purification

Molecular Weight

87

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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