TLK1 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to TLK1.Serine/threonine-protein kinase tousled-like 1 (TLK1) belongs to the protein kinase superfamily, Ser/Thr protein kinase family. TLK1 can be rapidly and transiently inhibited by phosphorylationfollowing the generation of DNA double-stranded breaks (DSBs) during S-phase. This event is cellcycle checkpoint and A-pathway dependent and appears to regulate processes involved inchromatin assembly. TLK1 exists in several isoforms, and Isoform 3 protects the cells from theionizing radiation by faciliting the repair of DSBs.
Product Specifications
Product Name Alternative
UniProt
Q9UKI8
Reactivity
Human, Mouse
Immunogen
N-terminal region of human TLK1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
87
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
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