SOCS6 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to SOCS6.Suppressor of cytokine signaling 6 (SOCS6) is a member of the SOCS family proteins that form partof a classical negative feedback system that regulates cytokine signal transduction. SOCS6 may be asubstrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomaldegradation of target proteins. SOCS6 regulates the degradation of the tyrosine-phosphorylated KITreceptor by ubiquitination.
Product Specifications
Product Name Alternative
UniProt
O14544
Reactivity
Human, Mouse
Immunogen
C-terminal region of human SOCS6
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
60
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
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