SMAD6 (M) Antibody, Rabbit Polyclonal
Rabbit polyclonal to SMAD6.Mothers against decapentaplegic homolog 6 (SMAD6) belongs to the dwarfin/SMAD family. SMAD6 isan antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamilymembers; it has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling bycompeting with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (ISMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.
Product Specifications
Product Name Alternative
UniProt
O43541
Reactivity
Human
Immunogen
Middle region of human SMAD6
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer, Cardiovascular Disease, Epigenetics, Stem Cells
Dilution
WB:1:500-1:1000
Purity
Affinity purification
Molecular Weight
53
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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