MKRN1 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to MKRN1.E3 ubiquitin-protein ligase makorin-1 (MKRN1) catalyzes the covalent attachment of ubiquitin moietiesonto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. MKRN1supports cell survival by suppressing p53/TP53 under normal conditions, but stimulates apoptosis byrepressing CDKN1A under stress conditions. MKRN1 acts as a negative regulator of telomerase andhas negative and positive effects on RNA polymerase II-dependent transcription.
Product Specifications
Product Name Alternative
Anti-MKRN1 antibody, anti-E3 ubiquitinprotein ligase makorin1 antibody, anti-RING finger protein 61 antibody, anti-RNF61 antibody
UniProt
Q9UHC7
Reactivity
Human, Mouse
Immunogen
N-terminal region of human MKRN1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
53
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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