CCR7 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to CCR7.C-C chemokine receptor type 7 (CCR7) is a receptor for the MIP-3-beta chemokine and belongs tothe G-protein coupled receptor 1 family. CCR7 was identified as a gene induced by the Epstein-Barrvirus (EBV) and is a probable mediator of EBV effects on B-lymphocytes as well as of normallymphocyte functions. CCR7 is expressed in various lymphoid tissues and activates B and Tlymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as wellas to stimulate dendritic cell maturation. CCR7 is strongly up-regulated in B-cells infected withEpstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Product Specifications
UniProt
P32248
Reactivity
Human
Immunogen
N-terminal region of human CCR7
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
43
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
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