CCR1 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to CCR1.C-C chemokine receptor type 1 (CCR1) is predicted to be a seven transmembrane protein similar to Gprotein-coupled receptors. It is a receptor for a C-C type chemokine. CCR1 binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequentlytransduces a signal by increasing the intracellular calcium ions level. It is responsible for affectingstem cell proliferation. Knockout studies of the mouse homolog suggested the roles of this gene inhost protection from inflammatory response, and susceptibility to virus and parasite.
Product Specifications
Product Name Alternative
UniProt
P32246
Reactivity
Human, Mouse
Immunogen
C-terminal region of human CCR1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
41
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
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