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PAX5 (C2) Antibody, Rabbit Polyclonal

Rabbit polyclonal to PAX5.PAX5 is a member of the paired box (PAX) family of transcription factors. The central feature of thisgene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteinsare important regulators in early development, and alterations in the expression of their genes arethought to contribute to neoplastic transformation. PAX5 is the B-cell lineage specific activator proteinexpressed at early, but not late stages of B-cell differentiation. PAX5 is also expressed in developingCNS and testis, suggesting a role of PAX5 in neural development and spermatogenesis. The PAX5gene is located at 9p13, which is involved in t (9;14) (p13; q32) translocations recurring in smalllymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.

Product Specifications

Product Name Alternative

Anti-PAX5 antibody, anti-Paired box protein Pax5 antibody, anti-Bcellspecific transcription factor antibody, anti-BSAP antibody

UniProt

Q02548

Reactivity

Human, Mouse

Immunogen

C-terminal region of human PAX5

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Neuroscience

Dilution

WB:1:1000-1:5000

Purity

Affinity purification

Molecular Weight

42

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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