NOTCH4 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to NOTCH4.Neurogenic locus notch homolog protein 4 (NOTCH4) is a single pass membrane protein that belongsto the NOTCH family. NOTCH4 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. NOTCH4 is cleaved upon ligand activationand the notch intracellular domain (NICD) is released, which forms a transcriptional activator complexwith RBPJ/RBPSUH to activate genes of the enhancer of split locus. It affects the implementation ofdifferentiation, proliferation and apoptotic programs.
Product Specifications
Product Name Alternative
Anti-NOTCH4 antibody, anti-Neurogenic locus notch homolog protein 4 antibody, anti-Notch 4 antibody, anti-hNotch4 antibody, anti-INT3 antibody
UniProt
Q99466
Reactivity
Human
Immunogen
C-terminal region of human NOTCH4
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
210
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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