NUMB (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to NUMB.NUMB is a membrane-bound protein that has been shown to associate with EPS15, LNX1, andNOTCH1. NUMB is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells GCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. NUMB is not required for the proliferation of neural progenitor cells before the onsetof neurogenesis. NUMB is also involved postnatally in the subventricular zone (SVZ) neurogenesis byregulating SVZ neuroblasts survival and ependymal wall integrity. In addition, NUMB may mediatelocal repair of brain ventricular wall damage.
Product Specifications
Product Name Alternative
Anti-NUMB antibody, anti-Protein numb homolog antibody, anti-hNumb antibody, anti-Protein S171 antibody
UniProt
P49757
Reactivity
Human, Mouse
Immunogen
C-terminal region of human NUMB
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
71
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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